Email: nsargentini@atsu.edu Tel: 660-626-2474 Fax: 660-626-2523

A.T. Still University of Health Sciences Kirksville College of Osteopathic Medicine 800 W. Jefferson St. Kirksville, MO  63501

Education:

Ph.D. (Medical Microbiology): Stanford University, 1980 M.A. (Microbiology): Califronia State University - Fresno, 1973 B.S. (Zoology): Califronia State University - Fresno, 1969 Research Associate: Stanford University, Dept. of Radiation Oncology, Radiobiology Research Division, 1980 - 1991

Research Interests: Dr. Sargentini's long-term research goal is to understand the molecular basis of DNA repair and mutagenesis in the bacterium Escherichia coli as a model for understanding the basis of cancer in humans. Presently, he is involved in characterizing the structure and function of RadA protein. Dr. Sargentini participated in the discovery of the radA gene and now is trying to determine its role in DNA repair. His other main research focus has been gamma radiation mutagenesis and how radiation chemistry, DNA damage, DNA repair processes, and translesion DNA replication interact to produce the mutations that are observed. Mutation analysis has involved the DNA sequencing of lacI forward mutations and long deletions within a lacI-Z fusion target.

Research and Scholarly Activity
Publications, Grants, Abstracts, Presentations, Honors, and Service to the Research Community are maintained in a separate section for Research and Scholarship.